Annual report pursuant to Section 13 and 15(d)

Common Stock Options, Restricted Stock and Changes In Capitalization - Narrative (Details)

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Common Stock Options, Restricted Stock and Changes In Capitalization - Narrative (Details) - USD ($)
$ in Thousands
12 Months Ended 44 Months Ended
Dec. 21, 2016
Mar. 15, 2016
Jun. 12, 2015
Apr. 21, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2016
Apr. 19, 2013
Apr. 20, 2006
Apr. 19, 2006
Class of Stock [Line Items]                      
Granted for purchase of previous Plan's common stock (shares)         0 0 0        
Proceeds from issuance of common stock, net of offering costs and exercise of stock options $ 698,800 $ 411,700 $ 479,700 $ 501,800 $ 1,110,555 $ 981,568 $ 689        
Common Stock                      
Class of Stock [Line Items]                      
Issuance of common stock in public offering (shares) 33,350,000 16,905,000 11,500,000 10,925,000 50,255,000 22,425,000          
2005 Stock Incentive Plan | Common Stock                      
Class of Stock [Line Items]                      
Available for grant (shares)                   3,000,000 1,904,606
Granted for purchase of previous Plan's common stock (shares)         997,269            
1999 Stock Option Plan | Common Stock                      
Class of Stock [Line Items]                      
Granted to employees under previous plan (shares)                   627,337  
2013 Restated Stock Incentive Plan | Common Stock                      
Class of Stock [Line Items]                      
Available for grant (shares)         1,062,207     1,062,207 7,500,000 3,000,000  
Granted for purchase of previous Plan's common stock (shares)               627,337      
Restricted stock | 2005 Stock Incentive Plan                      
Class of Stock [Line Items]                      
Granted for purchase of previous Plan's common stock (shares)         1,143,217            
Over-Allotment Option | Common Stock                      
Class of Stock [Line Items]                      
Issuance of common stock in public offering (shares) 4,350,000 2,205,000